Description
Short Description: Recombinant KMT2A (MLL1) complex contains amino acids 3735-3973 of the human MLL1 protein (accession number NP_001184033.1) with N-terminal GST-Tag and MW = 53.7 kDa; full-length human WDR5 (accession number NM_017588), with N-terminal 6xHis-tag and MW = 35 kDa; full-length human ASH2L (accession number NM_001105214), N-terminal 6xHis-tag and MW = 61 kDa; full-length human RbBP5 (accession number NM_005057), N-terminal 6xHis-tag and MW = 60 kDa, and full-length human DPY30 (accession number NM_032574), N-terminal 6xHis-tag and MW =12 kDa, all individually expressed in E Coli. The recombinant protein is >=95% pure by SDS-PAGE. It is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling